Endocrine Abstracts

Objective: To study the differences in the metabolic profile of patients with non-functioning adrenal adenomas (NFA) and autonomous cortisol secretion (ACS).Methods: 143 patients diagnosed of adrenal incidentaloma (AI) between 2010 and 2018 were retrospectively analyzed. AI was defined as an adrenal mass≥1 cm, accidentally discovered by radiologic examination. ACS was confirmed by serum cortisol post-dexamethasone suppression test (Nugent)≥3 ...

Introduction: Tumors derived from the extra-adrenal paraganglionic system are rare (incidence: 0.8/100,000 people/year). In this group, 85% are located in the abdomen, 12% in the thorax, and 3% in the head and neck region (HNPC).Case report: A 46-year-old man, ex-smoker, with a personal history of arterial hypertension, multifactorial secondary polycythemia (obesity, OSA syndrome, hypertrophic cardiomyopathy). Family history: one brother with paraganglio...

Introduction: Graves’ orbitopathy (GO) is the most common extrathyroidal manifestation of Graves’ disease. The first-line treatment are intravenous corticoids in active moderate-severe GO. Tocilizumab is a humanized monoclonal antibody against the IL-6 receptor which has been approved for the treatment of rheumatoid arthritis and is in its research stage for patients with corticosteroid-refractory GO.Objectives: To assess the experience with to...

PurposeTo assess the risk of developing hypercortisolism and/or tumor growth in non-functioning adrenal incidentalomas (NFAIs) during follow-up.MethodsSeven Spanish institutions participated in this retrospective study for patients with AIs. 1097 patients with one or more AIs ≥ 1 cm evaluated by participating physicians between 2013 and 2020 were subject to inclusion. Patients with missing values in the...